Starting in place of Oronde Gadsden, who was out with pneumonia, Chambers caught three passes for 49 yards and also returned the second-half kickoff 37 yards to set up a field goal.
Chambers' best play may have been a short catch he made in traffic in the second quarter. After making the catch, he broke a tackle and sprinted downfield for a 26-yard gain.
The other highlight Saturday was the running of Lamar Smith. Looking in midseason form, Smith carried the ball only five times against Green Bay, but had gains of 16 and 20 before leaving the game in the first half.
He also turned a sure loss on a screen pass into a 15-yard gain by breaking a tackle behind the line of scrimmage.
Despite the play of Smith and Chambers, the Dolphins' first-team offense wasn't nearly as sharp as it had been in the first three preseason games.
The first drive, in particular, was ugly. Guard Mark Dixon was called for holding and guard Todd Perry was called for being illegally downfield on the next play, a penalty that wiped out a long gain by Smith on a screen pass.
Jay Fiedler wasn't quite as sharp as he had been in previous week, as he finished 14-of-25 for 136 yards with one interception. In fairness, he was hurt by a couple of drops, and the culprits included fullback Rob Konrad, wide receiver James McKnight and Chambers.
The offense, in fact, could never reach the end zone against the Packers despite moving inside the 20-yard line four different times. All of Miami's scoring came on field goals Olindo Mare, who showed no ill effects from the foot injury that has caused him some pain in recent weeks.
Mare did miss a 36-yard attempt in the first half, but that happened because holder Matt Turk dropped the snap and killed Mare's timing.
As for the defense, the Dolphins were very shaky in the first and fourth quarters and brilliant in the second and third.
The first play from scrimmage in the game resulted in a 23-yard pass from Brett Favre to Bill Schroeder, and that set up a Ryan Longwell field goal.
Green Bay marched 62 yards on its next possession to take a 10-0 lead on Favre's 16-yard touchdown pass to Corey Bradford. One play in the drive that illustrated just how poorly things were going for the Dolphins early occurred when defensive end Kenny Mixon was offside and cornerback Terry Cousin was called for a 16-yard pass interference.
But after those first two Packers drive, the Dolphins allowed only 53 yards until the fourth quarter and came up with two turnovers, an interception by Cousin and a fumble recovery by linebacker Tyrus McCloud.
Mare's four field goals gave the Dolphins the lead heading into the fourth quarter, but Green Bay rallied after DeMond Parker broke loose for a 53-yard run on a draw play. The run gave the Pack a first-and-goal from the Dolphins 9-yard line, and Parker scored on a 4-yard sweep two plays later.
The Dolphins' final chance to come back ended when Green Bay ran out the clock after Herbert Goodman ran for 32 yards around left end on a third-and-11 from the 15-yard line.