Chambers, who won NFL Offensive Rookie of the Month honors in November of 2001, is the first Dolphins player to earn AFC Offensive Player of the Week accolades since quarterback Jay Fiedler in week 13 of 2003, in a 40-21 win at Dallas on November 27.
Chambers is the first Dolphins wide receiver to win the award since Mark Ingram in week 13 of 1994, in a 28-24 victory over the New York Jets at the Meadowlands.
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Nose tackle Keith Traylor likely will miss Sunday's game at San Diego after undergoing minor surgery on his right knee.
Traylor will be evaluated on a week-to-week basis.