"Obviously, I will be excited, but I'm not really nervous about messing up or anything like that. I'm just going to try to do what I can to help the team."
Williams knows all eyes will be on him when the defense hits the field in the sold out Reliant Stadium. Williams has been a hot topic ever since the Texans decided to bypass Reggie Bush in favor of Williams in the April draft.
Williams will start at right end for the Texans after spending much of the preseason at left end. He was moved around during each preseason game, and played inside in pass-rushing situations.
Williams rarely made highlight-reel plays, but he did impress his coaches by tying up blockers and opening up opportunities for his other teammates to make plays.
Williams' focus this week will be on helping the Texans pressure Eagles quarterback Donovan McNabb - a player with whom Williams is somewhat familiar.
"Well I play with him on Madden so. ... " Williams said. "But he's a great player, and it's going to be a challenge, a challenge that we all, as a unit, try to contain or try to stop him, or slow him down at least."
When asked how Williams fared against McNabb in the video game, Williams admitted he hopes Sunday goes better.
"I could never get to him," he said.