Hamilton's MRI came back Monday night and showed what everyone had feared – he had ruptured his right Achilles' tendon and would be sidelined no less than four months.
"Of course it's unfortunate," Hamilton said. "But that's part of the deal.
"Life goes on; the Giants are going to go on and Keith Hamilton has to go on."
Hamilton is scheduled to undergo surgery either Thursday or Friday.
Hamilton, who said he thought he was injured when teammate Lance Legree fell on the back of his right leg, said that he's been through much worse things in his life and plans to "fight like hell to come back."
However, he seemed unsure if the Giants would want him back. He referred to himself as a 32-year-old who's been hurt the last two seasons, and makes $3 million a year.
"It's always a possibility (that his injury is career-ending)," Hamilton said. "It might be a decision that comes down to the Giants. Whatever their decision is, they've been great to me."