Depleted LBs

As the Giants feared all week, Antonio Pierce was unable to play against San Francisco due to a quad injury. Chase Blackburn took his place as the starting MLB. Also, as expected, Gerris Wilkinson was sidelined due to a knee injury. Rookie Bryan Kehl started in his place.

The rest of the inactives were K Lawrence Tynes, CB R.W. McQuarters, RB Danny Ware, OT Adam Koets, WR Sinorice Moss and DE Jerome McDougle.

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