Two very evenly matched teams with a pair of great running backs. Mistakes will determine this one and the Titans will make one more mistake. Jaguars 20, Titans 14.
Pittsburgh (+1.5) @ Baltimore
The Ravens never beat the Steelers in big games and opening day is a big game. Give me the better team with points any day. Steelers 27, Ravens 14
Detroit @ Tampa Bay (-1.5)
I know the Lions are the chic playoff pick but Tampa Bay will have a great advantage playing at home in the heat. Josh Freeman will not let Matt Stafford upstage him. Bucs 20, Lions 17
Atlanta (-2) @ Chicago
Atlanta played a lot of close games last year and their style of play would suggest the same in 2011. The Falcons are a better team and their front four will put pressure on Jay Cutler. Falcons 21, Bears 17.
Buffalo (+5.5) @ Kansas City
The Bills have the better of the two quarterbacks and that should be good enough to stay close. Chiefs 24, Bills 21.
Indianapolis (+9) @ Houston
This Indianapolis Colts team has plenty of pride and a chip on their shoulders as most experts are predicting a last place finish without Peyton Manning. Colts keep it close. Texans 24, Colts 17.
Philadelphia @ St. Louis (+4)
The "Dream Team" will get tested by the Rams well-balanced offense and we like St. Louis to not only beat the spread, but pull the upset. Rams 21, Eagles 20
Cincinnati @ Cleveland (-6.5)
A rookie quarterback making his first start on the road against a pretty solid defense. Browns 26, Bengals 9.
N.Y. Giants @ Washington (+3)
Call me crazy but I'm betting on Rex Grossman, at least for one week. This feels like a trap game and there is simply too many injuries for the Giants defense. Redskins 21, Giants 16
Carolina @ Arizona (-7)
Cam Newton was terrible as a pocket passer in preseason. It's hard to believe that he'll improve significantly on the road in the regular season. Cardinals 30, Panthers 6.
Seattle (+5.5) @ San Francisco
These are two teams clearly in the hunt for Andrew Luck. Anytime we can get 5.5 points against San Francisco we'll take those points. 49ers 14, Seahawks 10.
Minnesota (+8.5) @ San Diego
The Chargers are a much better team than the Vikings, but Norv Turner is the ultimate equalizer. Chargers 24, Vikings 17.
Dallas (+5.5) @ N.Y. Jets
The Jets are more bark than bite, the Cowboys are underrated (is this a parallel universe?). Cowboys 21, Jets 20
New England @ Miami (+7)
This spread feels like a trap. Miami is a little better than many people believe and they always play the Patriots tough. Patriots 27, Dolphins 23.
Oakland @ Denver (-3)
Denver has the better quarterback in Kyle Orton, better coach in John Fox and they're playing at home. I'll lay the points. Broncos 34, Raiders 17.
Charlie Bernstein is the NFL Insider for ESPN 1080 and 1040 in Orlando/Tampa and the host of "The Sports Crunch" on the Aquarius 7 Broadcasting Network (national), and Editor-in-Chief of Sports Media Interactive, covering multiple teams in the National Football League, NCAA, and National Basketball Association. Charlie covers the Jacksonville Jaguars for FoxSports and has been featured on the NFL Network and Sirius NFL Radio. Charlie is also a member of the Pro Football Writers of America. You can follow Charlie on Twitter @nflcharlie
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