The Jaguars went into the game with a 6-4 mark, dropped to 6-5 and finished 8-8 while missing the playoffs by a game.
They lost the game on a Rian Lindell 42-yard field goal as time expired.
On Sunday, the Jaguars will play host to the Bills and they can all but wrap up a playoff berth with a victory.
This time, the Jaguars come into the game with a 7-3 mark after beating the San Diego Chargers, 24-17, last Sunday.
And since they have Carolina, Oakland and Houston left on the schedule, a victory would put them into position to finish 11-5 even if they lose on the road to Indianapolis and Pittsburgh.
But they could be caught looking past Buffalo because they play Indianapolis in two weeks. Since they Jaguars are only a game behind the Colts, they could have a shot to tie the Colts for the division lead in two weeks if they beat Buffalo.
The Jaguars also have to worry about the injury bug. They lost linebacker Mike Peterson for several weeks when he broke several bones in his hand. And cornerback Rashean Mathis suffered a groin strain, but the Jaguars hope it's not serious.
To offset the injuries, they have quarterback David Garrard and kicker Josh Scobee back for their stretch run.
Garrard returned after missing three games with a high ankle sprain and showed he wasn't rusty after the layoff.
He had a 114.8 quarterback rating as he threw for two touchdowns. He has yet to throw an interception in seven games.
Scobee hadn't kicked since the opener against Tennessee when he strained a quad muscle in the pre-game warm-ups.
He booted a 48-yard field goal at the end of the Jaguars' first series of the game when coach Jack Del Rio declined to go for it on 4th-and-3.
When John Carney, who no longer has a big leg, was filling in for Scobee, Del Rio often went for it on fourth down.
On the Jaguars' second possession, the Jaguars first lined up for a field goal on 4th-and-1. But after calling a time out, the Jaguars went for it when Garrard got a yard on a quarterback sneak, although the Jaguars may have gotten a fortunate spot on the play as he made it by inches.
Four plays later on a fourth down at the one, the Jaguars went for it again and Maurice Jones-Drew scored the touchdown that gave the Jaguars a 10-0 lead and they controlled the game.
Score to Settle Against Buffalo
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