Preview Friday: Week Four gives an inside look at what to expect from the Bills this Sunday as the 2-1 Jets look to extend their perfect record in division play.

THE OVERVIEW: Ryan Fitzpatrick threw a touchdown to Lee Evans in what was perhaps the Jets' worst loss last season, a 16-13 overtime stinker at The Meadowlands in a game that saw Mark Sanchez throw five interceptions. Sanchez threw for a pedestrian 7-for-15 with 105 yards and a touchdown in his second game against the Bills, though Braylon Edwards dropped a sure touchdown bomb and Sanchez was injured in the second half.

Yep, that right there is the definition of not a good day.

The Jets vastly improved second-year quarterback will get another shot at the Bills this Sunday on the road, and Fitzpatrick, who replaced an injured Trent Edwards in the team's October meeting last season, is now calling signals for Buffalo as the starter. Fitzpatrick tossed two touchdowns and two interceptions while amassing 247 yards in New England last week, and Sanchez, who has thrown no interceptions this season, is coming off his second straight three-touchdown performance.

WHEN THE BILLS HAVE THE BALL: Jets Head Coach Rex Ryan said New York's third-down defense (which ranks second-to-last in the NFL with opposing teams moving the chains 51 percent of the time) will be one of the best this season. New York will get a chance to improve that number against a Buffalo offense that will rely on the running game. The Jets aren't where they want to be in terms of defensive rankings, but they are still fourth against the run, holding teams' rushing attacks to 61.7 yards per game. Bills rookie C.J. Spiller, who had a stellar preseason, ran back a kick return for a touchdown last week and had a 19-yard gain on a rushing play. Running back Marshawn Lynch also had a decent game, picking up 79 yards on 13 carries.

Buffalo could be in trouble if it has to go to the passing game, though Fitzpatrick won't have to throw against cornerback Darrelle Revis, who will miss another week due to a hamstring injury. Drew Coleman will most likely be taking the outside corner spot opposite Antonio Cromartie, as the Jets have decided to keep rookie cornerback Kyle Wilson covering the slot. Expect the Jets to stuff the run early and heavily blitz Fitzpatrick until he proves he can beat them. New York should be able to set the tone early.

WHEN THE JETS HAVE THE BALL: Sanchez said his terrible game against Buffalo last season was "like your dog died. It was the worst." Don't expect him to feel that way Sunday night. Sanchez is red hot right now, leading New York's offense as the sixth-rated passer in the NFL at 104.6. New York rushed for more than 300 yards in its first meeting with the Bills in 2009, and Buffalo is ranked 27th against the run this season. Expect the Jets to ground and pound at will. Shonn Greene will probably see more touches than he has in the past three games, and Ryan even said rookie Joe McKnight may be activated come kickoff time.

It would be ideal for the Jets to give Sanchez some passing series in order to keep him in the mode. Buffalo ranked second against the pass last year and led the league in interceptions, but the complete secondary that returned from a season ago hasn't been as successful in 2010, and it may be without its top cornerback in Terrence McGee, who is dealing with knee soreness. Marcus Stroud and linebacker Andra Davis will be out for the game, but the Bills do expect Paul Posluszy back Sunday. The Jets doubled the Patriots' points in the teams' meetings, and New England put up 38 against the Bills last week. Buffalo will have a hard time stopping a rather surprising offense given its Week 1 performance against the Ravens.

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