Brown was signed to a one-year, $1 million contract as a free agent, but hasn't been a solid fit with the Eagles' offense.
In six games, he has rushed for only 38 yards on 13 carries with one lost fumble. He's averaging just 2.9 yards per carry.
Brown is a former Miami Dolphins starter and first-round draft pick from Auburn.
The Lions were looking for a running back due to Jahvid Best's concussion.
Harrison has previously played for the Cleveland Browns and the Eagles.
He has gained only 41 yards on 14 carries in four games this season for the Lions.
However, he did rush for 239 yards and one touchdown last season in Philadelphia. Harrison also caught eight passes for 43 yards.
For his career, he has rushed for 1,681 yards and seven touchdowns with 70 receptions for 590 yards and three scores.
For more coverage of the NFL, go to profootball.scout.com.
Follow me on Twitter: @RavensInsider
Eagles trade Ronnie Brown for Jerome Harrison
Lions Report Top Stories
2017 Fantasy Football PrimerAre you ready for the 2017 Fantasy Football season? It can't come soon enough, right? This page is a hub where we both want to look forward towards 2017 but also look back at 2016.
Scout FantasyWednesday at 1:26 PM
'17 Draft Will Make or Break Lions FutureLions General Manager Bob Quinn took the controls in Detroit during the start of the 2016 offseason. One year later, he could be at a cross roads with one path leading towards…
Jarrad Davis to the Lions in the first roundWith the 21st pick of the first round, the Detroit Lions selected Florida’s middle linebacker Jarrad Davis.
How Will Devin Taylor Factor Into the DefenseThe New York Giants signed former Lion Devin Taylor to a one-year contract, providing depth to a rather thin defensive line.
The Giants BeatYesterday at 10:15 AM
CF.C honored for excellence in journalismBIG SHOUT OUT today to Barry Bolton, Jed Collins and Skyler Cracraft. For the third-straight year, Cougfan.com dominated the sports writing category in the Society of Professional…
CougfanThursday at 2:59 PM