Green's 154-yard effort on 27 leg-churning carries keyed the Packers past the San Francisco 49ers 20-10 in a crucial NFC matchup Nov. 23 at soggy Lambeau Field.
It was Green's eighth 100-plus rushing game of the year — a new team record — and lifted his season total to 1,326 yards.
He also moved past John Brockington into second-place in team history in career rushing yards gained with 5,128 and was within 148 yards of tying Jim Taylor for the most rushing yards gained in a season heading into the Packers' Thanksgiving Day showdown with NFC North rival Detroit.
"It's the old cliche: Records are made to be broken,'" said Green. "I'm proud of it. But I'm just in a long line of great backs to have played here. I've still got a job to do."
Green did a job on the 49ers, punishing a defensive unit that was giving up just 86.9 yards per game.
Whether it was taking a toss, scooting around the edge or simply blasting through a hole up the gut, the 49ers didn't have the answer on how to slow Green, even when they loaded up eight in a box.
It was Green's fourth straight 100-yard game, an all-time Packers record, and it left him within range of reaching 2,000 yards for the season.
Following the victory, Green needed 674 more yards to reach 2,000, or an average of 134.8 per game.
"We feel we can run the ball every week," center Mike Flanagan said. "We've got the talent up front, we've got the backs, we've got the game plan. As long as we execute, we're a tough team to beat."
Overall, the Packers rushed for 243 yards on 48 carries. It was the fourth time this season Green Bay has rushed for 200 or more yards in a game. Against Tampa Bay on Nov. 16, Green Bay rushed for 190 yards.
"I don't mind it a bit," Favre said when asked to talk about how the team has relied on the run more than the pass this season. "When we're running the way we are, you have one-on-one situations sometimes. You kind of lie and wait, which is not a bad thing to do."
That was what occurred on the Packers' third offensive play of the game. Following a pair of Green runs, Green Bay was facing a third-and-five from its own 34-yard line.
Catching the Niners in a one-on-one situation, Favre lofted a pass downfield to receiver Javon Walker, who was able to get in front of Niners' cornerback Jason Webster and make an over-the-shoulder catch.
From there, Walker tip-toed down the left sideline and eventually scored from 66 yards out.
"You have to respect everything," right tackle Mark Tauscher said. "We're in a zone as far as what we want to do. Up front, we're covering people up, and our backs are just making great decisions."
Starting with Green, who moved into second all-time behind Taylor for the most team career rushing yards with 5,128 and fifth all-time in total yards with 7,002.
"My goals aren't yards," said Green, who leads the team with 14 touchdowns scored, including 10 rushing. "My goal is how many games we need to win to get to the playoffs and the Super Bowl. The yards will come with it."