Charlotte, NC - The Panthers/Cardinals series is tied at 1-1. The most recent match-up was last season's 30-7 loss.
Lamar Smith needs two touchdown runs to pass the late Fred Lane for the Panthers' single season rushing touchdown record.
Panthers' owner Jerry Richardson will miss his first game at Ericsson Stadium while hospitalized for chills and a high fever.
Despite a compound fracture of the ring finger on his right hand (which required stitches), Wesley Walls is expected to play Sunday.
The 2-2 Cardinals rank 25th in league offense and defense.
So far, the Panthers are undefeated at home in this young season.
The premiere match-up of the day should be Arizona's mammoth offensive line (averaging 320 pounds per man) against Carolina's fast, sack-happy defensive line (averaging 294.5 pounds per man). Whichever team gets the upper hand in this trench battle could control the game.
ARIZONA CARDINALS (2-2) AT CAROLINA PANTHERS (3-1)
OUT - T Anthony Clement (arm); RB Dennis McKinley (hamstring); CB Duane Starks (groin)
DOUBTFUL - LB Levar Fisher (knee); RB Marcel Shipp (knee)
QUESTIONABLE - RB Thomas Jones (ankle)
PROBABLE - G Chris Dishman (concussion); C Mike Gruttadauria (back); T L.J. Shelton (ankle)
OUT - RB Deshaun Foster (knee)
DOUBTFUL - WR Muhsin Muhammad (hamstring)
QUESTIONABLE - RB Nick Goings (ribs)
PROBABLE - DT Brentson Buckner (toe); DT Sean Gilbert (knee); C Jeff Mitchell (ankle); QB Rodney Peete (knee); DE Mike Rucker (ankle); T Todd Steussie (ankle); DE Al Wallace (knee); TE Wesley Walls (knee)