Buffalo (4-8) hosts the two-time defending Super Bowl champion New England Patriots (7-5), who can clinch in the AFC East title for the fourth time in five seasons with a victory coupled with a loss by Miami (5-7) at San Diego.
If the Bills can pull off the upset -- New England has won nine of the past 10 games in the series -- they then face another tough test against Denver (9-3) at home, then comes a road game at Cincinnati (9-3).
After a meeting with Moulds and coach Mike Mularkey on Thursday, Bills owner Ralph Wilson announced that Moulds was suspended without pay for Sunday's game, a sanction that apparently stemmed from Moulds' incident with receivers coach Tyke Tolbert on the sideline last Sunday. Moulds' adviser, Greg Johnson, told the Associated Press that Moulds will accept the suspension and will watch this week's game as "a fan" and "cheer on" the Bills.
Earlier Thursday, television crews were staked out at the stadium on what is normally a slow day. Sports talk shows debated who's to blame for Buffalo's current state. One newspaper ran a poll asking whom Wilson should fire: general manager Tom Donahoe, Mularkey or Moulds. Donahoe was leading with 66 percent.
"There's a lot of chaos," running back Willis McGahee said. "You don't know what to expect right now at this point."
"There are always ebbs and flows in a season, good stuff and some bad stuff," defensive tackle Justin Bannan added. "The main thing is sticking together as a team and getting through the rough times and enjoying the good times."
Bannan said that as players, the Bills can't lose their focus worrying about Moulds' fate.
"I just want to take care of what I've got to take care of," he said. "We do that on this team, we should be OK. We all have to look in the mirror and try and do better, because were not cutting it right now."