Oakland is ranked No. 31 in run defense, allowing 143.8 yards per game, and is dead last in terms of yards per carry (4.7) and rushing touchdowns (21).
The Raiders broke from form against the Colts, giving up 58 yards on 20 carries, a 2.9-yard average, and holding Joseph Addai to 44 yards on 15 attempts.
It was the lowest rushing yardage figure by an opponent all season and only the third time under 100 yards. Oakland has given up 100 yards rushing to nine different backs, and opponents have broken 175 yards against them five times.
Kiffin acknowledged that in terms of style, the Raiders matched up better with the Colts than they do with the Jaguars.
"It was a spread out style, we played man coverage and were able to keep them outnumbered inside," Kiffin said. "We don't deal with a fullback and lead plays. This week presents a totally new challenge -- two backs in the backfield, coming downhill."
The Jaguars are second in the NFL in rushing with 2,094 yards, trailing only Minnesota, and have 471 rushing plays -- the most in the league. Ten-year veteran Fred Taylor has rushed for 1,091 yards and a 5.1 average, with second-year back Maurice Jones Drew adding 725 yards and a 4.6 average.
The Jaguars are coming off a 29-22 win in Pittsburgh in which they punctured one of the NFL's top run defenses for 224 yards. Free safety Hiram Eugene knows what's coming.
"Looking back at what we've been going through, teams have been putting a lot of rushing yards on us," Eugene said. "They're going to come right at us."
Defensive coordinator Rob Ryan showed his defense film of the Jaguars running the ball on 14 consecutive plays.