Asomugha played the first two series and was flagged for illegal contact on Drew Brees' 40-yard touchdown throw to Devery Henderson but did not return after that.
According to head coach Tom Cable, Asomugha suffered a left wrist chip fracture that the team believes isn't serious.
"Actually it didn't sound like he would miss much of anything," Cable said. "It's not that big a deal given where it's at and all of that."
Asomugha, who is normally one of the most quoted Oakland players after games, wasn't available and his stall was cleaned out long before the media was allowed into the Raiders locker room.
If Cable is correct and Asomugha's injury isn't serious, Oakland is still likely to hold the veteran cornerback out of the preseason finale against Seattle next week as a precaution.
Asomugha has been battling shoulder and heel pains throughout training camp.
Asomugha injured in preseason loss to Saints
Oakland Raiders Top Stories
2017 Fantasy Football PrimerAre you ready for the 2017 Fantasy Football season? It can't come soon enough, right? This page is a hub where we both want to look forward towards 2017 but also look back at 2016.
Scout FantasyYesterday at 1:26 PM
Amari Cooper named 53rd-best in NFLOakland Raiders wide receiver Amari Cooper is voted the 53rd-best player in the NFL by his peers on "Top 100 Players of 2017."
Oakland RaidersMonday at 7:36 PM
Carr reportedly 'frustrated' with contractRaiders Derek Carr reportedly 'frustrated' with contract talks
LISTEN: Which AFC West Teams Improved?Carl Dumler and Nick Kendell share some immediate thoughts on the Denver Broncos draft haul, before going around the AFC West to see how the competition shaped up. Which Divisional…
Mile High Huddle05/05/2017