The rookie quarterback, who completed 32 of 55 pass attempts for 253 yards with one touchdown and three interceptions in his debut against the Cardinals, knows the Rams will have a difficult test this week.
"They are going to challenge us," he said. "They are going to get in our face. They are going to play a lot of man coverage. Obviously Nnamdi (Asomugha) is one of the best corners in the league. So we have to be very careful the way that we plan to attack them. But if they do come up and play man, we have to be able to beat their coverage."
One interesting sidenote to this week's matchup is that one of the Raiders backup quarterbacks is Kyle Boller, who played with the Rams last season and learned the ins and the outs of the St. Louis offense.
The Rams will be trying to avoid starting out the seasons with back-to-back losses.
"No one wants to start 0-2," Bradford said. "No one wants to start 0-1. Going into last week we thought we had a great chance to win that football game and we did. Unfortunately things didn't go our way and we didn't get the win."