This week, the challenge will get tougher.
Oher, who is expected to start again in place of the injured Jared Gaither, will line up against Minnesota Vikings defensive end Jared Allen. Through five weeks of the regular season, Allen has become the front-runner for NFL Defensive Player of the Year.
"There are guys that are sort of like him, but there's nobody with a higher motor," Ravens coach John Harbaugh said. "Jared Allen just brings it every single play.
"He's explosive, he's physical, he's got spin moves, he's got hump moves, he's got every kind of move that you could think of. Really what makes him so good is his relentlessness as a pass rusher and a run defender. We respect him a lot."
Since being acquired in a trade from the Kansas City Chiefs for a first-round draft pick and two third-round draft picks, Allen has emerged as the scourge of the league when it comes to harassing quarterbacks. Now, Allen is the Ravens' big problem to deal with as they'll do everything they can to try to contain him during Sunday's matchup at the Metrodome.
Regardless of whether Oher squares off with Allen as the Ravens' starting left offensive tackle or if Gaither somehow recovers in time for kickoff, the Ravens definitely have a tough assignment.
"He's a highlight reel," Oher said. "He has every move. You have to study everything he does."
Allen absolutely dismantled the Green Bay Packers two weeks ago with 4.5 sacks. He sacked and stripped Packers quarterback Aaron Rodgers in tandem with Brian Robison, registering three solo sacks and a coverage sack on his own despite chip-blocking assistance and Green Bay designing rollouts to avoid his presence.
"He's a great player, the best I've ever seen personally," Oher said. "You have to get after him and just stay with your fundamental technique. You have to play very fast.
"He's a tough guy, he's a fast guy. He's very physical. I've seen everything from him. He's very athletic and he has a motor."
The Vikings value Allen so highly that they signed him to a six-year, $72.3 million contract. Allen rewarded that faith by recording 14.5 sacks last season.
This year, the 27-year-old already has 6.5 sacks and three forced fumbles with one safety.
"He's obviously had a really good season," said Ravens quarterback Joe Flacco, the chief target of Allen's pursuit Sunday. "He's played well for a while now, so we're going to go into the game and we're going to have specific plans for their defense.
"They have a bunch of guys on their front seven that can get after it and we're going to be accounting for every one of them."
Ravens offensive coordinator Cam Cameron is quite familiar with Allen. When Cameron had the same role for the San Diego Chargers, he used to game plan against Allen twice a season when he was a pass rusher for the Kansas City Chiefs.
"Indoors on turf is even more of a challenge than outdoors in Kansas City, when we played him there," Cameron said. "He is one of those high-motor guys that is just a great player, end of story. He loves to play the game."